Extracellular Matrix Proteins
Tags
Human Cellular Fibronectin Extracellular Matrix Proteins Bovine Plasma Vitronectin Bovine Plasma Fibronectin

Achieving physiologically relevant in vitro models is paramount for groundbreaking research. The extracellular matrix (ECM) plays a critical role in cell behavior, influencing everything from adhesion and spreading to growth and differentiation. 

 

To provide your cells with the optimal environment, ScienCell offers a selection of highly purified ECM proteins designed to serve as effective cell culture substrata. Our ECM proteins are:

  • Validated through wet lab-based cell attachment assays
  • Supports consistent and uniform cell populations
  • Delivers reproducible experimental outcomes
  • Economical solution for scalable cell culture applications

Discover the difference these specialized proteins can make in your experiments! 
 

Human Cellular Fibronectin (HCF, Cat. No. 8488)

 

  • HCF differs from plasma fibronectin through the presence of additional polypeptide segments
  • Crucially, HCF has the capacity to specifically regulate the morphology and growth of attached cells, including stem cells. This distinction makes it particularly valuable for certain research applications
  • It is produced from human fibroblasts maintained in serum-free media and purified biochemically
  • Fibronectin matrix assembly is essential for normal development and also contributes to tumor metastases

Bovine Plasma Fibronectin (BPF, Cat. No. 8248)

 

  • Purified from bovine plasma using affinity chromatography
  • BPF is recommended for use as a cell culture substratum
  • Its primary function is to support cell adhesion and spreading on the culture dish
  • BPF binds to cell membrane receptors and extracellular matrix components

Bovine Plasma Vitronectin (BPV, Cat. No. 8538)

 

  • Vitronectin is another important glycoprotein found in plasma and the extracellular matrix
  • BPV is purified from bovine plasma by affinity chromatography
  • Vitronectin is involved in a wide range of biological functions, including cell adhesion, spreading, migration, proliferation, extracellular anchoring, fibrinolysis, hemostasis, and complement immune defense
  • It can be effectively used for coating tissue culture surfaces to promote cell adhesion, proliferation, and differentiation

Simplified Preparation & Quality You Can Trust

 

All ScienCell ECM proteins are supplied sterile and come with straightforward coating instructions

 

By incorporating ScienCell's high-quality Human Cellular Fibronectin, Bovine Plasma Fibronectin, or Bovine Plasma Vitronectin into your workflow, you can provide your cells with the essential environmental cues needed for improved attachment, growth, and function, leading to more reliable and relevant experimental outcomes.