Animal Dermal Fibroblasts

Unraveling Cellular Dynamics: Explore Dermal Fibroblasts from ScienCell!

Fibroblasts, fundamental mesenchymal cells derived from the embryonic mesoderm, are widely utilized in cellular and molecular research due to their ease of culture and robust nature. These versatile cells are key secretors of a non-rigid extracellular matrix, abundant in type I and/or type III collagen, making them essential for tissue structure and repair.

 

Among their diverse roles, dermal fibroblasts are particularly fascinating. Found within the skin's dermis layer, they exhibit a dynamic ability to transition between a proliferative, migratory state and a contractile, matrix-remodeling phase, which is critical during wound healing processes. This makes them an invaluable in vitro model for studying a spectrum of physiological and pathological conditions.

Bovine Dermal Fibroblasts 

(BDF, Catalog No. B2300)

  • Isolated from bovine skin
  • Cryopreserved at passage one and delivered frozen
  • Each vial contains >5 x 105 cells in 1 ml volume

Research Applications: A useful in vitro model to study the mechanisms of wound healing and to develop therapeutic targets aimed at reducing scarring and fibrosis.

Rabbit Dermal Fibroblasts 

(RabDF, Catalog No. Rab2300)

  • Isolated from rabbit skin
  • Cryopreserved at passage one and delivered frozen
  • Each vial contains >5 x 105 cells in 1 ml volume

Research Applications: Rabbit Dermal Fibroblasts provide a useful in vitro model for exploring wound healing and dermal fibrosis.

Rat Dermal Fibroblasts 

(RDF, Catalog No. R2300)

  • Isolated from neonatal rat skin
  • Cryopreserved at P0 and delivered frozen
  • Each vial contains >5 x 105 cells in 1 ml volume

Research Applications: A valuable in vitro model for wound healing and inflammation studies.

Mouse Dermal Fibroblasts

(MDF, Catalog No. M2300)

  • Isolated from postnatal day 2 CD-1 mouse skin
  • Cryopreserved at passage one and delivered frozen
  • Each vial contains >5 x 105 cells in 1 ml volume

Research Applications: A useful in vitro model to further study skin disease, skin aging, and the wound healing process.

 

Also available: Mouse Dermal Fibroblasts from C57BL/6
(Cat. No. M2300-57)