Monthly Archives: January 2024
-
- 一月 03, 2024
The ocular lens is a transparent structure in the eye that is designed to refract and focus light onto the retina. The lens is an avascular unit which includes the lens capsule, lens epithelium, and lens fibers. Lens fiber cells form the bulk of the lens and a monolayer of epithelial cells cover the anterior surface of the fibers. Lens epithelial cells perform a number of critical functions in the lens including the growth and development of the lens, fluid transport, protecting the lens from environmental and oxidative stress, and maintaining the homeostasis of the lens. Lens epithelial cells are also critical for metabolic activity in the ocular lens, and this activity can be affected by epithelial cell differentiation. During development, lens epithelial cells migrate from the equatorial region to the interior to produce transparent crystallins and develop into lens fiber cells. The crystallins help to maintain the transparency of the lens, but during aging are modified or degraded resulting
