Cell Based Assays

  1. A Groundbreaking Discovery in T Cell Telomere Aging

    A Groundbreaking Discovery in T Cell Telomere Aging

    Telomere “caps” are located at the ends of all chromosomes, including those of the immune system’s T-lymphocytes (T cells), and become shorter with every cell division. Once these chromosomes reach a point where the telomere is too short to provide adequate protection, division ceases and the cell proceeds

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  2. What Role do Alveolar Epithelial Cells Play in COVID-19 Disease Progression?

    Alveolar Epithelial Cells

    SARS-CoV-2 is the seventh known coronavirus that causes the human disease known as COVID-19. The virus can grow in cells lining the conducting airways and in alveolar epithelial cells. First, the virus generally enters the body through the nose or mouth. From there, the virus travels down into the alveoli

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  3. Gain New Biological Insights with Ready-To-Use Spheroids

    Gain New Biological Insights with Ready-To-Use Spheroids

    Traditional 2D cultures have been used widely over the past decades to study cell biology, molecular biology and conduct translation research such as drug discovery. Cells in 2D culture, however, are forced to adopt a planar morphology and maintain cellular interactions only in lateral directions, altering

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  4. Why comparing Cell Viability, Proliferation and Apoptosis?

    cell division

    Cell-based assays are widely used in basic and translational research as cost-effective and accessible models to mimic in vivo responses. To obtain reliable data, assessing the health of cultured cells prior to any assays is highly recommended. Furthermore, many cell-based assays require quantification

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  5. Not All Primary Cells are Created Equal.

    Not All Primary Cells are Created Equal.

    Primary cells, which are isolated directly from tissue, show normal cell morphology and maintain many of the important markers and functions seen in vivo. Primary cells, though, have a finite lifespan and limited expansion capacity, so it is critical to use low passage primary cells for your research.

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  6. Welcome to the 3rd Dimension

    Welcome to the 3rd Dimension

    Cell culturing is a widely used technique to grow cells outside of their natural environment using artificial environments and controlled conditions that has become indispensable to scientific research.  The applications of cell culturing are innumerable and there are many ways to differentiate types

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  7. Perspectives on Cancer

    Perspectives on Cancer

    Cancer is a collection of over 200 diseases where the only common denominator is rogue cells1,2.  The ways in which a cell can go rogue is so varied that cancer has its own separate biology where order and normalcy are not readily apparent.  Cancer does not even have to be solid.  Indeed, blood

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  8. Comparison of Cell Viability, Proliferation and Apoptosis Assays

    Comparison of Cell Viability, Proliferation and Apoptosis Assays

    Cell-based assays are widely used in basic and translational research as cost-effective and accessible models to mimic in vivo responses. To obtain reliable data, assessing the health of cultured cells prior to any assays is essential. Furthermore, many cell-based assays require quantification of cell

    完整阅读 »