Monthly Archives: July 2016
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- 七月 05, 2016
Recently, bone marrow mononuclear cells (BMMC) have been in the spotlight for having the potential to treat a variety of diseases including neurological disorders. Why are BMMC so exciting and do they really show treatment potential? BMMC have regenerative capabilities and are a heterogeneous population of single nucleus cells which include hematopoietic progenitor cells, immature monocytes and lymphocytes, and importantly hematopoietic stem cells. Hematopoietic stem cells have the ability to self-renew and can differentiate into a variety of cell types. Recent studies with animal models show great promise for BMMC in multiple sclerosis, Alzheimer’s disease, ischemic stroke, cardiovascular disease, and type-1 diabetes. BMMC may also be utilized for bone tissue engineering. To date, preliminary human clinical trials indicate treating patients with ischemic vascular disease, peripheral arterial disease, bone nonunion, or pressure ulcers using autologous BMMC appear promising. Encouragingly,
