Monthly Archives: June 2016
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- 六月 07, 2016
Despite being essential for any experiment involving DNA replication, people rarely give primers a second thought. To coincide with the launch of our new qPCR gene reference tool, we’ll be giving them a little more of the praise they deserve.
Dr Kary Mullis received the 1993 Nobel Prize in Chemistry for his contributions toward developing the PCR.Primers are the foundation for such grand purposes as diagnosing diseases, tracking epidemics, creating phylogenetic trees, genetic fingerprinting, and cloning a woolly mammoth. On a smaller but no-less grand scale, these simple 15-30 nucleotide sequences are widely used to assess cell phenotypes, identify signal transduction aberrancies, perform functional gene analyses, and study molecular pathologies. The most common research application of primers today is probably in performing the polymerase chain reaction (PCR) to amplify or replicate a targeted DNA sequence. Like the humble primer, the PCR’s advent revolutionized scientific