Monthly Archives: March 2025
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- March 25, 2025
The fourth Tuesday in March is #AmericanDiabetesAlertDay. Today, we highlight this global health concern and emerging standards of care for type 1 and type 2 diabetes mellitus, and how #primarycellmodels might support the ongoing research to combat these diseases.
Though characterized by dysfunction of pancreatic beta cells and hyperglycemia, #diabetes is a multisystem #metabolicdisorder affecting the adipose tissue, cardiovascular system, liver, and reproductive systems. [1] The strong correlation between obesity and type 2 diabetes has led to the rise of glucagon-like peptide 1 receptor (GLP1R) agonists approved first for type 2 diabetes treatment, and now for obesity treatment. [2] The most widely used #GLP-1 medications, #dulaglutide, #semaglutide, and #tirzepatide, have proven to reduce HbA1c levels and obesity. Beyond improvements in glucose control and weight management, GLP-1Ras have shown evidence-based reduction in major adverse cardiovascular events (#MACE), heart failure,
