drug discovery

Parkinson’s disease research has long centered on one highly vulnerable cell type: the midbrain dopaminergic neuron. These neurons control key aspects of movement, reward, and motivation, and their progressive degeneration in the substantia nigra is one of the defining features of Parkinson’s disease.

Evaluate cAMP-dependent signaling with ScienCell’s CRE/CREB Dual Reporter Vector (CREVR, Cat. No. VT004). CREB regulates gene expression in response to cAMP/PKA, calcium, and other signaling pathways, controlling metabolism, neuronal activity, and stress responses. Accurate measurement of CRE activity