Hepatic sinusoidal endothelial cells (HSEC) are fascinating cells that are uniquely adapted to their location in the liver. HSEC are found lining micro-vessels in the liver and are extremely specialized… Read more »
SARS-CoV-2 is the seventh known coronavirus that causes the human disease known as COVID-19. The virus can grow in cells lining the conducting airways and in alveolar epithelial cells. First,… Read more »
As of April 10, 2020, the number of U.S. SARS-CoV-2 coronavirus cases surpassed 500,000 with a death toll near 19,000. For over a century, coronaviruses were thought to only cause… Read more »
Traditional 2D cultures have been used widely over the past decades to study cell biology, molecular biology and conduct translation research such as drug discovery. Cells in 2D culture, however,… Read more »
Primary cells, which are isolated directly from tissue, show normal cell morphology and maintain many of the important markers and functions seen in vivo. Primary cells, though, have a finite lifespan and limited expansion capacity, so it is critical to use primary cells at low passage for your research.
Neuronal cell lines are commonly used for in vitro neurobiology studies because they are more easily transfected compared to primary neurons and they proliferate, whereas primary neurons do not. Neuronal… Read more »