Isolation of high-quality nucleic acids from biological material is a key factor in successful molecular biology research. While approaches vary, most methods aim to do the following: (1) disrupt the… Read more »
Telomere “caps” are located at the ends of all chromosomes, including those of the immune system’s T-lymphocytes (T cells), and become shorter with every cell division. Once these chromosomes reach… Read more »
Microglia play an essential role in brain homeostasis, neuroinflammation, neurodegenerative diseases, and brain infections. Microglia are integral components of the neuro-glial cell network and are the resident immune cells of… Read more »
Hepatic sinusoidal endothelial cells (HSEC) are fascinating cells that are uniquely adapted to their location in the liver. HSEC are found lining micro-vessels in the liver and are extremely specialized… Read more »
SARS-CoV-2 is the seventh known coronavirus that causes the human disease known as COVID-19. The virus can grow in cells lining the conducting airways and in alveolar epithelial cells. First,… Read more »
Epithelial cells are the most numerous cells in the lungs and contribute to innate and adaptive immunity. Airway epithelial cells are located in the lower respiratory tract which includes the… Read more »
As of April 10, 2020, the number of U.S. SARS-CoV-2 coronavirus cases surpassed 500,000 with a death toll near 19,000. For over a century, coronaviruses were thought to only cause… Read more »
Migraines and headaches can be extremely debilitating with a diverse set of triggers and symptoms. Although the pathophysiology for headaches is still unclear, evidence suggests that factors such as neurogenic… Read more »
Traditional 2D cultures have been used widely over the past decades to study cell biology, molecular biology and conduct translation research such as drug discovery. Cells in 2D culture, however,… Read more »
Hepatic stellate cells have recently gained a great deal of attention regarding their contribution to the progression of diseases such as liver fibrosis, non-alcoholic steatohepatitis (NASH), and hepatocellular carcinoma. Hepatic… Read more »