Animal Stem Cells

Are you at the forefront of veterinary science research, seeking innovative tools for regenerative medicine and a deeper understanding of species biology? Look no further! ScienCell Research Laboratories offers a range of primary mesenchymal stem cells (MSCs) derived from various animal species, providing valuable resources for your investigations.

Potential of Veterinary Regenerative Medicine

• Mesenchymal stem cells (MSCs), a proliferative population of multipotent stem cells, hold immense promise for regenerative medicine in animals
• These cells possess the remarkable ability to develop into mature cells that produce fat, cartilage, bone, tendons, and muscle. This developmental plasticity is key to their potential in replacing damaged tissues in animal subjects
• With their renewal capability, these MSCs have the potential to be transplanted into an injured site in animal models to facilitate tissue repair
• They can also be seeded on biomimetic scaffolds to generate appropriate tissue constructs for veterinary applications
• Culturing MSCs under specific conditions can direct their differentiation into desired cell types, such as chondrocytes in the presence of transformation growth factors without serum or osteoblasts when cultured in serum with ascorbic acid and dexamethasone

Compare Species Homology with Stem Cells from Unique Animal Donors

• ScienCell offers MSCs derived from dog adipose tissue (DMSC-ad), horse adipose tissue (HMSC-ad) and rat bone marrow (RMSC-bm)
• These species-specific stem cells provide a unique opportunity to compare cellular characteristics and differentiation potential across different animal models.
• Researchers can investigate conserved and divergent mechanisms in stem cell biology and their response to various stimuli, contributing to a better understanding of species homology at the cellular level.
• Characterization data, such as immunofluorescence with antibodies specific to CD90 for DMSC-ad and HMSC-ad and CD73 and/or CD90 for RMSC-bm along with Oil Red O staining after adipogenic differentiation and Alizarin Red staining after osteogenic differentiation for RMSC-bm provide valuable insights for comparative studies 

Establish Cell Therapy Model Cultures In Vitro

• ScienCell's cryopreserved MSCs, delivered frozen at passage one are guaranteed to further culture under recommended conditions
• These cultures serve as excellent cell therapy models to study cell behavior, differentiation pathways, and responses to potential therapeutic agents before in vivo application.
• The ability to subculture these cells allows for the generation of sufficient cell numbers for various experimental designs and the development of scalable cell therapy strategies for veterinary applications.
• Recommended media, such as Mesenchymal Stem Cell Medium (MSCM, Cat. #7501) ensure optimal growth and maintenance of these primary cell cultures.