Recombinant Human Transforming Growth Factor-β2
Recombinant Human TGF-β2 consists of two identical 112-amino acid polypeptide chains connected by a single disulfide bond and has a molecular weight of 24.0 kDa.
Related Promotion:
There are three mammalian isoforms of transforming growth factor-beta (TGF-β), namely TGF-β1, TGF-β2, and TGF-β3. These multifunctional cytokines signal through the same receptor and elicit similar biological responses. They play crucial roles in regulating cell proliferation, growth, differentiation, motility, and the synthesis and deposition of the extracellular matrix. The release of the biologically active TGF-β isoform from a latent complex involves intracellular proteolytic processing. TGF beta 1, TGF beta 2, and TGF beta 1.2 exhibit similar biological activities, although they differ in receptor binding affinities. TGF beta 2 is found in high concentrations in platelets and bone. It is the prominent isoform in body fluids like amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye. Recombinant Human TGF-β2 consists of two identical 112-amino acid polypeptide chains connected by a single disulfide bond and has a molecular weight of 24.0 kDa.
| Catalog No. | 105-52 |
|---|---|
| Product Code | rhTGFb2 |
| Size/Quantity | 10 ug, 25 ug, 100 ug |
| Product use | This product is for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures. |
| Storage | Upon receipt, store at -20°C after receiving. Upon reconstitution, store at 2-8°C for up to one week. For maximal stability, aliquot and store at -20°C. Avoid repeated freeze/ thaw cycles. |
| Shipping | Gel Pack |
| Synonyms | Transforming Growth Factor-β2, Glioblastoma-derived T-cell suppressor factor, G-TSF, BSC-1 cell growth inhibitor, Polyergin, Cetermin |
| AA Sequence | ALDAAYCFRN VQDNCCLRPL YIDFKRDLGW KWIHEPKGYN ANFCAGACPY LWSSDTQHSR VLSLYNTINPE ASASPCCVSQ DLEPLTILYYI GKTPKIEQLSN MIVKSCKCS |
| Source | mammalian cell |
| Molecular Weight | 24.0 kDa, a disulfide bond linked non-glycosylated polypeptide chains containing two 112 amino acids |
| Purity | > 95% |
| Physical Appearance | Light yellow to white powder |
| Formulation | Lyophilized from a 0.2μm filtered concentrated (1mg/ml) solution in 30 mM Glycine-HCl and 100 mM NaCl with dextran as protectant. |
| Endotoxin | <0.1 ng/μg of protein (<1 EU/μg) |
| Reconstitution | Reconstitute in sterile distilled water or 0.04 M HCl containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |
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