Recombinant Human UbE2R2
ScienCell’s Recombinant Human UbE2R2 (6xHis-UbE2R2) is for research use only. It is not approved for human or animal use, or for application in clinical or in vitro diagnostic procedures.
Recombinant Human UbE2R2 is an E2 ubiquitin-conjugating enzyme involved in the ubiquitin-proteasome pathway. As a component of the E1–E2–E3 enzymatic cascade, it participates in the transfer of ubiquitin to target proteins. CK2-mediated phosphorylation of UbE2R2 is required for its association with the β-TrCP-containing SCF E3 ligase complex. UbE2R2 primarily catalyzes the formation of K48-linked polyubiquitin chains, which serve as degradation signals for proteasomal turnover of substrate proteins.
This recombinant protein contains an N-terminal 6×His tag and a thrombin cleavage sequence for convenient purification and downstream applications.
| 目录编号 | MB7538 |
|---|---|
| 制造国家 | 美国 |
| 产品编码 | 6xHis-UbE2R2 |
| 规格/数量 | 25 ug or 100 ug |
| 产品用途 | This product is for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures. |
| 储存 | Upon receipt, store at -20°C in a manual defrost freezer. |
| 运输 | Dry ice. |
| Synonyms | UBC3B; CDC34B; E2-CDC34B; FLJ20419; MGC10481 |
| AA Sequence | MGSSHHHHHH SSGLVPRGSH MAQQQMTSSQ KALMLELKSL QEEPVEGFRI TLVDESDLYN WEVAIFGPPN TLYEGGYFKA HIKFPIDYPY SPPTFRFLTK MWHPNIYENG DVCISILHPP VDDPQSGELP SERWNPTQNV RTILLSVISL LNEPNTFSPA NVDASVMFRK WRDSKGKDKE YAEIIRKQVS ATKAEAEKDG VKVPTTLAEY CIKTKVPSND NSSDLLYDDL YDDDIDDEDE EEEDADCYDD DDSGNEES |
| Source | Escherichia coli |
| Molecular Weight | 29.3 kDa, a single non-glycosylated polypeptide chain containing 258 amino acids |
| Purity | > 90% |
