人小气道上皮细胞（成人）
ScienCell Research Laboratories 的人小气道上皮细胞（成人）（HPSAEpiC-a）分离自人成人肺组织。HPSAEpiC-a 以第 1 代（P1）冻存，并以冷冻状态运输。每瓶含有 >5 × 105 个细胞，体积为 1 ml。
The small airways are located at the interface between alveoli and conducting airways. Airway epithelial cells form a continuous lining in the airways and play a unique role as a protective physical and functional barrier to external deleterious agents. Small airway epithelial cells (SAEpiC) regulate the immune responses by contributing to host defense through chemokine production and adhesion molecule expression. They also produce liquids contributing to pulmonary fluid balance. Many airway diseases, such as asthma, bronchiolitis, chronic obstructive pulmonary disease, and cystic fibrosis, involve damage to the airway surface epithelium. The study of human SAEpiC may help to identify new therapeutic options for preventing airway disorders.
HPSAEpiC-a from ScienCell Research Laboratories are isolated from human adult lung tissue. HPSAEpiC-a are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. HPSAEpiC-a are characterized by immunofluorescence with antibodies specific to cytokeratin-18 and/or cytokeratin-19. HPSAEpiC-a are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HPSAEpiC-a are guaranteed to further expand for 15 population doublings under the conditions provided by ScienCell Research Laboratories.
Recommended Medium
It is recommended to use Small Airway Epithelial Cell Medium (SAEpiCM, Cat. #3231) for culturing HPSAEpiC-a in vitro.
小气道位于肺泡与传导性气道之间的过渡区域。气道上皮细胞连续覆盖于气道表面，在抵御外界有害物质的过程中发挥独特的保护作用，构成重要的物理和功能屏障。小气道上皮细胞（SAEpiC）通过产生趋化因子和表达黏附分子参与宿主防御，从而调节免疫反应。此外，小气道上皮细胞还能分泌液体，参与维持肺部液体平衡。哮喘、细支气管炎、慢性阻塞性肺疾病（COPD）和囊性纤维化等多种气道疾病均与气道表面上皮损伤有关。对人小气道上皮细胞的研究有助于探索预防和治疗气道疾病的新方法。
ScienCell Research Laboratories 的人小气道上皮细胞（成人）（HPSAEpiC-a）分离自人成人肺组织。HPSAEpiC-a 以第 1 代（P1）冻存，并以冷冻状态运输。每瓶含有 >5 × 105 个细胞，体积为 1 ml。HPSAEpiC-a 采用针对细胞角蛋白-18（cytokeratin-18）和/或细胞角蛋白-19（cytokeratin-19）的特异性抗体进行免疫荧光鉴定。HPSAEpiC-a 经检测对 HIV-1、HBV、HCV、支原体、细菌、酵母菌和真菌均呈阴性。在 ScienCell Research Laboratories 提供的培养条件下，HPSAEpiC-a 可进一步扩增 15 个群体倍增（population doublings）。
推荐培养基
推荐使用小气道上皮细胞培养基（SAEpiCM，产品编号：3231）在体外培养 HPSAEpiC-a。
| 目录编号 | 3250 |
|---|---|
| 制造国家 | 美国 |
| 产品编码 | HPSAEpiC-a |
| 规格/数量 | Each vial contains >5 x 10^5 cells in 1 ml volume. |
| 产品用途 | 本产品仅供研究使用。未经批准，不得用于人体、动物或体外诊断程序。 |
| 储存 | 收到后，立即将细胞从干冰转移到液氮中，并在液氮中保存，直到需要进行实验。 |
| 运输 | 干冰。 |
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