三维基础型管状结构包埋形成试剂盒

Collagen is a major structural component in the extracellular matrix (ECM) and in connective tissues such as tendons, ligaments, dermis, and blood vessels. As insoluble fibrous proteins, collagens are the primary determinant of ECM tensile strength and they help tissues withstand stretching. While there are at least 28 types of collagen, 80-90% of the collagen in the human body are types I, II, and III. The 3D Basic Embedded Tubule Formation Kit (3D-BETF) contains collagen type I, which is found in skin, tendon, vasculature, and bone ECM, as well as the accessory components needed to form a 3D collagen gel matrix. It also includes a serum free assay medium optimized to promote endothelial tubule formation within the collagen gels. Note: This kit does not include cells. For inclusive kits to create 3-dimensional scaffolds that includes primary cells, see ScienCell™’s 3D Embedded Tubule Formation Kit (Cat. #8708), ScienCell™’s Network Formation Assay Kit (Cat. #8718), and ScienCell™’s Endothelial–Pericyte Coculturing Kit (Cat. #8728).

胶原蛋白是细胞外基质（ECM）及肌腱、韧带、真皮和血管等结缔组织中的主要结构成分。胶原蛋白属于不溶性纤维状蛋白质，是决定细胞外基质抗拉强度的关键因素，有助于组织抵抗拉伸作用。胶原蛋白至少有 28 种类型，其中 I 型、II 型和 III 型胶原蛋白约占人体胶原蛋白总量的 80%–90%。

三维基础型管状结构包埋形成试剂盒（3D-BETF）包含 I 型胶原蛋白，该蛋白存在于皮肤、肌腱、血管及骨组织的细胞外基质（ECM）中。试剂盒还包含形成三维胶原蛋白凝胶基质所需的辅助组分，以及一种无血清检测培养基。该培养基经过优化，可促进内皮细胞在胶原蛋白凝胶中形成管状结构。

注意：本试剂盒不包含细胞。如需使用原代细胞构建三维支架，可参考 ScienCell™ 的以下配套试剂盒：三维管状结构包埋形成试剂盒（产品编号：8708）、网络形成实验试剂盒（产品编号：8718）以及内皮细胞–周细胞共培养试剂盒（产品编号：8728）。

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