Neurological Disease Therapy through Regulation of Reactive Oxygen Species Levels

ScienCell’s Rat Hippocampal Neurons Used in Recent Neurological Disease Therapy Research Published in Scientific Reports Journal

Neurons are dynamically polarized cells responsible for electrochemically transmitting information throughout the nervous system. Scientists have characterized hundreds of neuron types based on location, morphology and gene expression. In general, there are three main types of neurons: motor neurons, sensory neurons, and interneurons. Despite great variability in size and shape, most neurons share common morphological features including a cell body, dendrites, the axon, and the axon terminals.

Researchers at Nanjing University, Jiangsu University and Jiangsu Province Hospital of Chinese Medicine used ScienCell’s Rat Hippocampal Neurons in their research on neuroprotection by polynitrogen manganese complexes: regulation of ROS-related pathways. Through this study, they found that due to ROS either inducing cellular oxidative stress or increasing cell tolerance against insult when cell death occurs, neurologic diseases may potentially be treated by regulating ROS levels in a certain range with small molecules.

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Neurons can be used to study:

Alzheimer’s disease, dementia, Parkinson’s disease, Huntington’s disease, bipolar disorder, addiction, traumatic brain injury, and spinal cord injuries. Learn more >>


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