Telomeres are repetitive nucleotide elements at the ends of chromosomes that protect chromosomes from degradation and genetic information loss. Telomere shortening has negative effects on health conditions and has been linked to many health issues including aging and cancer. Accurate and consistent quantification of telomere length is important in many aspects of cell biology such as chromosomal instability, DNA repair, senescence, apoptosis, cell dysfunctions, and oncogenesis.
ScienCell exclusively offers qPCR-based assay kits for the accurate, simple, and fast telomere length quantification of various species samples:
Absolute
Includes a reference gDNA sample with known telomere length. This kit can be used to calculate a sample’s actual telomere length in kb.
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▪ Absolute Human Telomere Length Quantification qPCR Assay Kit (Cat.# 8918)
▪ Absolute Mouse Telomere Length Quantification qPCR Assay Kit (Cat.# M8918)
▪ Absolute Rat Telomere Length Quantification qPCR Assay Kit (Cat.#R8918)
▪ Absolute Bovine Telomere Length Quantification qPCR Assay Kit (Cat.#B8918)
▪ Absolute Pig Telomere Length Quantification qPCR Assay Kit (Cat.#P8918)
Relative
NO reference gDNA sample included. Can be used to compare the telomere length of samples in fold change.
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▪ Relative Human Telomere Length Quantification qPCR Assay Kit (Cat.# 8908)
▪ Relative Mouse Telomere Length Quantification qPCR Assay Kit (Cat.# M8908)
▪ Relative Rat Telomere Length Quantification qPCR Assay Kit (Cat.# R8908)
PRODUCT CHARACTERISTICS:
• Unique: specially modified primers only available at ScienCell
• Accurate: highly specific and qPCR efficiency close to 100%
• Reliable: NO detectable primer dimer formation after 28-30 cycles
• Informative: telomere length expressed in kilobases (Cat. #8918 only)
• Sensitive: as low as 0.1 ng of gDNA required
• Convenient: NO special treatment of gDNA necessary
• Rapid: results can be acquired within 1 hour
• Robust: suitable for a high-throughput setup