Recombinant Human Growth Hormone
Recombinant Human Growth Hormone (rhGH) product is a member of a family of growth factors. Research use only. Synthesized and shipped on gel packs
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Human Growth Hormone (GH) is a member of a family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. It is synthesized primarily by somatotropes in the anterior pituitary and is stored in secretary granules. The pulsatile release of GH into circulation is regulated by the concerted actions of the hypothalamic hormones-GH-releasing hormone (GHRH) and somatostatin (SST) - as well as by signals from the periphery - ghrelin and leptin.4 The human GH cDNA encodes a 217 amino acid (aa) residue precursor protein with a 26 aa putative signal peptide. By alternative splicing, at least four αsoforms of GH have been identified.
Shipping and Storage
rhGH is shipped on gel pack. Upon receipt, store at -20oC after receiving. Upon reconstitution, store at 2-8 oC for up to one week. For maximal stability, aliquot and store at -20oC. Avoid repeated freeze/ thaw cycles.Usage
rhGH is for research use only. rhGH is not approved for human or animal use, or for application in clinical or in vitro diagnostic procedures| Catalog No. | 301-01 |
|---|---|
| Product Code | rhGH |
| Country of Manufacture | United States or China |
| Size/Quantity | 20ug, 500ug, or 1mg |
| Product use | This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. |
| Storage | Store at -20°C after receiving. Upon reconstitution, store at 2-8°C for up to one week. For maximal stability, aliquot and store at -20°C. Avoid repeated freeze/ thaw cycles. |
| Shipping | Dry ice. |
| Synonyms | Somatotropin, GHN, GH-N, hGH-N, IGHD1B, pituitary growth hormone |
| AA Sequence | SFPTIPLSRLF DNAMLRAHRL HQLAFDTYQE FEEAYIPKEQ KYSFLQNPQTSLCFSESIPT PSNREETQQK SNLELLRISL LLIQSWLEPV QFLRSVFANSLVYGASDSNV YDLLKDLEEG IQTLMGRLED GSPRTGQIFK QTYSKFDTNSHNDDALLKNY GLLYCFRKDM DKVETFLRIV QCRSVEGSCG F |
| Source | Escherichia coli |
| Molecular Weight | Approximately 22 kDa, a single non-glycosylated polypeptide chain containing 192 amino acids |
| Purity | >95% by SDS-PAGE |
| Physical Appearance | White lyophilized powder. |
| Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4 containing 2% dextran as protectant |
| Endotoxin | <0.1 ng/μg of protein (<1 EU/μg) |
| Reconstitution | Reconstitute in sterile distilled water containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |
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