Human Cardiac Fibroblasts-adult (HCF-a) - Immunostaining for Vimentin, 200x.

Human Cardiac Fibroblasts-adult

Name: Human Cardiac Fibroblasts-adult
Brand: Sciencell Research Laboratories
SKU: 6330
Price: 860 USD
Availability: OutOfStock

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Catalog No.

6330

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Isolated from human adult heart. HCF-a are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10⁵ cells in 1 ml volume.

Product Description

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Technical Resources

Product Reviews

Publications

Cardiac fibroblasts (CF) provide structural support for cardiac myocytes and are responsible for extracellular matrix synthesis in the heart during growth and pathophysiological conditions. CF are an important cellular component of myocardial responses to injury and the source of paracrine growth factors. CF proliferation and synthesis of matrix is essential for scar formation at sites of myocardial infarction and cardiac fibrosis. CF cultures have been widely used as a model to study the cardiac matrix remodeling by physiological (exercise) and pathological (hypertension) stressors.

HCF-a from ScienCell Research Laboratories are isolated from human adult heart. HCF-a are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10⁵ cells in 1 ml volume. HCF-a are characterized by immunofluorescence with antibody specific to fibronectin. HCF-a are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HCF-a are guaranteed to further expand for 15 population doublings under the conditions provided by ScienCell Research Laboratories.

Recommended Medium

It is recommended to use Fibroblast Medium-2 (FM-2, Cat. #2331) for culturing HCF-a in vitro.

More Information
Catalog No.	6330
Country of Manufacture	United States
Product Code	HCF-a
Size/Quantity	5 x 10^5 cells/vial
Product use	This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.
Storage	Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.
Shipping	Dry ice.

1. Widjaja, A.A., Lim, WW., Viswanathan, S. et al. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature (2024).

For healthspan and lifespan, ERK, AMPK and mTORC1 represent critical pathways and inflammation is a centrally important hallmark1,2,3,4,5,6,7. Here we examined whether IL... More

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