Recombinant Human Interleukin-3
The human IL-3 reported to be a monomer. Specifically, human and murine IL-3 share low homology and it does not show activity on murine cells.
Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) which is encoded by the IL-3 gene located on chromosome 5 and produced primarily by activated T cells beside human thymic epithelial cells, activated murine mast cells, murine keratinocytes and neurons/astrocytes. The protein acts in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. The human IL-3 reported to be a monomer. Specifically, human and murine IL-3 share low homology and it does not show activity on murine cells
| Catalog No. | 101-03 |
|---|---|
| Country of Manufacture | United States |
| Product Code | rhIL-3 |
| Size/Quantity | 10 μg, 100 μg, or 1 mg |
| Product use | This product is for research use only. It is not approved for human or animal use, or for application in vitro diagnostic procedures. |
| Storage | Upon receipt, store at -20°C after receiving. Upon reconstitution, store at 2-8 °C for up to one week. For maximal stability, aliquot and store at -20 °C. Avoid repeated freeze/ thaw cycles. |
| Shipping | Gel pack |
| Synonyms | Hematopoietic growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor |
| AA Sequence | SAPMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF |
| Source | Escherichia coli |
| Molecular Weight | 15.4 kDa, a single non-glycosylated polypeptide chain containing 134 amino acids |
| Purity | > 95% |
| Physical Appearance | White lyophilized powder. |
| Formulation | Lyophilized from a 0.2µm filtered concentrated (1mg/ml) solution in PBS, pH 7.4. |
| Endotoxin | <0.1 ng/μg of protein (<1 EU/μg) |
| Reconstitution | Reconstitute in sterile distilled water containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |
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