Recombinant Human Apo Transferrin
Transferrin is the iron-transport protein of vertebrate serum and donates iron to cells through interaction with a specific membrane receptor, CD71.
Transferrin is the iron-transport protein of vertebrate serum and donates iron to cells through interaction with a specific membrane receptor, CD71. Transferrin appears to be indispensable for most cells growing in tissue culture. It is referred to frequently as a growth factor because, in analogy to other growth factor-receptor interactions, proliferating cells express high numbers of transferrin receptors, and the binding of transferrin to their receptors is needed for cells to initiate and maintain their DNA synthesis. Apart from its role as an iron transport protein, transferrin acts as a cytokine and has functions that may not be related to its iron-carrying capacity. The recombinant human transferrin that is completely animal-free and blood-free. Its performance is equivalent to human transferrin in cell culture and offers significant regulatory advantages due to its safety and consistency.
| Catalog No. | MB9108 |
|---|---|
| Country of Manufacture | United States |
| Product Code | rhATF |
| Size/Quantity | 100 mg, 1000 mg |
| Product use | This product is for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures. |
| Storage | Store at -20°C after receiving. Upon reconstitution, store at 2-8°C for up to one week. For maximal stability, aliquot and store at -20°C. Avoid repeated freeze/ thaw cycles. |
| Shipping | Gel pack |
| Synonyms | Apo Transferrin, ATF |
| AA Sequence | SVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPS VACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYL APNNLKPVVAEFYGSKEVPQTFYYAVAVVKKDSGFQ MNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKP LEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLN QYFGYSGAFKCLKNGAGDVAFVKHSTIFENLANKADR DQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSM GGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDL LFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGT CQEAPTDECKPVKWCALSHHERLKCDEWSVNSVGKIE CVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCGL VPVLAENYNKSDNCEDTPEAGYFAVAVVKKSASDLT WDNLKGKKSCHTAVGRTAGWNIPMGLLYNKINHCRF DEFFSEGCAPGSKKDSSLCKLCMGSGLNLCEPNNKEG YYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDP WAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNH AVVTRKDKEACVHKILRQQQHLFGSNVTDCSGNFCLF RSETKDLLFRDDTVCLAKLHDRNTYEKYLGEEYVKAV GNLRKCSTSSLLEACTFRRP |
| Source | Yeast |
| Molecular Weight | Approximately 76 kDa. |
| Purity | > 95% by SDS-PAGE |
| Physical Appearance | White lyophilized powder. |
| Formulation | Lyophilized from a solution in water. |
| Endotoxin | <0.1 ng/μg of protein (<1 EU/μg) |
| Reconstitution | Reconstitute in distilled water or 1x PBS buffer containing 0.1% BSA to a concentration of 0.1-10.0 mg/mL. |
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