Recombinant Bovine Fibroblast Growth Factor-basic
This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.
Basic Fibroblast Growth Factor (bFGF) is a member of the FGF family of mitogenic peptides which is comprised of at least 23 proteins. FGF signaling factors play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. It was originally named bFGF based upon its chemical properties and to distinguish it from acidic fibroblast growth factor.
| Catalog No. | 154-02 |
|---|---|
| Product Code | rbbFGF |
| Country of Manufacture | United States or China |
| Size/Quantity | 10ug, 50ug, 1mg |
| Product use | This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. |
| Storage | Store at -20°C after receiving. Upon reconstitution, store at 2-8°C for up to one week. For maximal stability, aliquot and store at -20°C. Avoid repeated freeze/ thaw cycles. |
| Shipping | Dry ice. |
| Synonyms | FGF-2, Fibroblast Growth Factor basic (FGFb) |
| AA Sequence | MTMITNSSSV PGDPLESMAA GSITTLPALP EDGGSGAFPP GHFKDPKRLYCKNGGFFLRI HPDGRVDGVR EKSDPHIKLQ LQAEERGVVS IKGVCANRYLAMKEDGRLLA SKCVTDECFF FERLESNNYN TYRSRKYSSW YVALKRTGQYKLGPKTGPGQ KAILFLPMSA KS |
| Source | Escherichia coli |
| Molecular Weight | Approximately 18.5 kDa, a single non-glycosylated polypeptide chain containing 172 amino acids |
| Purity | >95% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active. The ED50 is < 1.0ng/ml, corresponding to a specific activity of 1.0×10^6 Units/mg, as determined by the proliferation of BALB/c 3T3 cells. |
| Physical Appearance | White lyophilized powder. |
| Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4, containing 4% mannitol. |
| Endotoxin | < 1EU/μg of growth factor as determined by LAL method. |
| Reconstitution | Reconstitute in sterile distilled water containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |
No Publication available at this time.