Recombinant Murine FGF
This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.
Murine basic fibroblast growth factor (bFGF or FGF-2) is a multifunctional protein crucial in mouse cellular biology. Expressed across various tissues, it lacks a typical secretory signal peptide and exists in multiple isoforms through alternative translation start sites. bFGF plays pivotal roles in cell proliferation, migration, differentiation, and angiogenesis, with significant involvement in embryonic stem cell maintenance and tissue development. It’s expression can be modulated by factors like stem cell factor and transforming growth factor-β, and it demonstrates important functions in both normal physiological processes and pathological conditions, such as cancer cell progression. The protein's diverse capabilities make it a key molecule in understanding mouse cellular mechanisms and potential therapeutic interventions.
| 目录编号 | 124-02 |
|---|---|
| 产品编码 | rmbFGF |
| 制造国家 | United States or China |
| 规格/数量 | 10ug, 50ug, 1mg |
| 产品用途 | 本产品仅供研究使用。未经批准，不得用于人体、动物或体外诊断程序。 |
| 储存 | 收到后，请储存于 -20°C。复溶后，可在 2-8°C 保存最多一周。为获得最大稳定性，请分装并储存于 -20°C。避免反复冻融。 |
| 运输 | 凝胶冰袋。 |
| Synonyms | bFGF, fibroblast growth factor basic |
| AA Sequence | SPALPEDGGA AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS |
| Source | E. coli |
| Purity | > 95% |
| Physical Appearance | Light yellow to white powder |
| Formulation | Lyophilized from a 0.2µm filtered concentrated (1mg/ml) solution in 1x PBS with dextran as protectant. |
| Endotoxin | <0.1 ng/μg of protein (<1 EU/μg) |
| Reconstitution | Reconstitute in sterile distilled water or sterile 1x PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |