Recombinant Human Placental Growth Hormone
Recombinant Human Placental Growth Hormone (rhPLGH) is for research use only. It is not approved for human or animal use, or for application in clinical or in vitro diagnostic procedures.
Placenta growth factor (PLGH) is a glycosylated homodimeric protein primarily expressed in the placenta, with lower levels found in the heart, lung, thyroid, skeletal muscle, and adipose tissue. In the placenta, PLGH acts in an autocrine manner on trophoblasts, which express both PLGH and its receptor VEGFR-1, influencing trophoblast growth, differentiation, and invasion. PLGH can form heterodimers with VEGF-A when co-expressed, activating VEGFR-1 and VEGFR-1/VEGFR-2 heterodimers. This growth factor play crucial roles in angiogenesis, lymphangiogenesis, and endothelial cell growth, contributing to placental development and function throughout gestation.
| 目录编号 | 105-24 |
|---|---|
| 制造国家 | 美国 |
| 产品编码 | rhPLGH |
| 规格/数量 | 10ug, 100ug, 1mg |
| 产品用途 | 本产品仅供研究使用。未经批准，不得用于人体、动物或体外诊断程序。 |
| 储存 | 收到后，请储存于 -20°C。复溶后，可在 2-8°C 保存最多一周。为获得最大稳定性，请分装并储存于 -20°C。避免反复冻融。 |
| 运输 | 凝胶包。 |
| Synonyms | PGH, PlGH, PlGF |
| AA Sequence | LPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR |
| Source | Yeast |
| Purity | > 95% |
| Physical Appearance | Light yellow to white powder |
| Formulation | Lyophilized from a 0.2μm filtered concentrated (1mg/ml) solution in 1x PBS with dextran as protectant. |
| Endotoxin | <0.1 ng/μg of protein (<1 EU/μg) |
| Reconstitution | Reconstitute in sterile distilled water or 1x PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |