Fibroblast Growth Factor 9 (FGF-9) is one of the 23 known members of the FGF family. All FGF family members are heparin binding growth factors with a core 120 amino acid FGF domain that allows for a common tertiary structure. FGF-9 targets glial cells, astrocytes cells and other cells that express the FGF receptor 1c, 2c, 3b, 3c, and 4.
成纤维细胞生长因子9(FGF-9)是已知的23种FGF家族成员之一。所有FGF家族成员均为肝素结合生长因子,具有一个核心的120个氨基酸的FGF结构域,使其具有共同的三级结构。FGF-9作用于胶质细胞、星形胶质细胞以及其他表达FGF受体1c、2c、3b、3c和4的细胞。
| 目录编号 | 104-09 |
|---|---|
| 制造国家 | 中国 |
| 产品编码 | rhFGF-9 |
| 规格/数量 | 5ug, 20ug, or 1mg |
| 产品用途 | 本产品仅供研究使用。未经批准,不得用于人体、动物或体外诊断程序。 |
| 储存 | 收到后,请储存于 -20°C。复溶后,可在 2-8°C 保存最多一周。为获得最大稳定性,请分装并储存于 -20°C。避免反复冻融。 |
| 运输 | 干冰。 |
| Synonyms | Glia-activating factor (GAF), HBGF-9, SYNS3 |
| AA Sequence | APLGEVGNYF GVQDAVPFGN VPVLPVDSPV LLSDHLGQSE AGGLPRGPAVTDLDHLKGIL RRRQLYCRTG FHLEIFPNGT IQGTRKDHSR FGILEFISIAVGLVSIRGVD SGLYLGMNEK GELYGSEKLT QECVFREQFE ENWYNTYSSNLYKHVDTGRR YYVALNKDGT PREGTRTKRH QKFTHFLPRP VDPDKVPELYKDILSQS |
| Source | Escherichia coli |
| Molecular Weight | Approximately 23.4 kDa, a single non-glycosylated polypeptide chain containing 207 amino acids. |
| Purity | >95% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active. The ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10^6 units/mg, as determined by proliferation of BaF3 cells expressing FGF receptors. |
| Physical Appearance | White lyophilized powder. |
| Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4. |
| Endotoxin | < 1EU/μg of growth factor as determined by LAL method. |
| Reconstitution | Reconstitute in sterile distilled water containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |