Recombinant Bovine Fibroblast Growth Factor-basic
This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.
Basic Fibroblast Growth Factor (bFGF) is a member of the FGF family of mitogenic peptides which is comprised of at least 23 proteins. FGF signaling factors play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. It was originally named bFGF based upon its chemical properties and to distinguish it from acidic fibroblast growth factor.
| 目录编号 | 154-02 |
|---|---|
| 产品编码 | rbbFGF |
| 制造国家 | United States or China |
| 规格/数量 | 10ug, 50ug, 1mg |
| 产品用途 | 本产品仅供研究使用。未经批准，不得用于人体、动物或体外诊断程序。 |
| 储存 | 收到后，请储存于 -20°C。复溶后，可在 2-8°C 保存最多一周。为获得最大稳定性，请分装并储存于 -20°C。避免反复冻融。 |
| 运输 | 干冰。 |
| Synonyms | FGF-2, Fibroblast Growth Factor basic (FGFb) |
| AA Sequence | MTMITNSSSV PGDPLESMAA GSITTLPALP EDGGSGAFPP GHFKDPKRLYCKNGGFFLRI HPDGRVDGVR EKSDPHIKLQ LQAEERGVVS IKGVCANRYLAMKEDGRLLA SKCVTDECFF FERLESNNYN TYRSRKYSSW YVALKRTGQYKLGPKTGPGQ KAILFLPMSA KS |
| Source | Escherichia coli |
| Molecular Weight | Approximately 18.5 kDa, a single non-glycosylated polypeptide chain containing 172 amino acids |
| Purity | >95% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active. The ED50 is < 1.0ng/ml, corresponding to a specific activity of 1.0×10^6 Units/mg, as determined by the proliferation of BALB/c 3T3 cells. |
| Physical Appearance | White lyophilized powder. |
| Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4, containing 4% mannitol. |
| Endotoxin | < 1EU/μg of growth factor as determined by LAL method. |
| Reconstitution | Reconstitute in sterile distilled water containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |