CD1小鼠骨髓单个核细胞

Bone Marrow Mononuclear Cells (BMMC) are located in the bone marrow and have regenerative capabilities. Primary BMMC are a heterogeneous population of single nucleus cells which include hematopoietic stem cells, hematopoietic progenitor cells, immature monocytes, and immature lymphocytes. Recent studies suggest that BMMC are suitable as a cell therapy to treat a variety of diseases such as cardiovascular disease, type 1 diabetes, and ischemic stroke. BMMC may also be used for bone tissue engineering. Primary mouse BMMC (MBMMC) can be utilized to further study BMMC as a potential cell therapy.

MBMMC from ScienCell Research Laboratories are isolated from healthy adult CD-1 mouse bone marrow. MBMMC are depleted of erythrocytes and bone marrow macrophages, cryopreserved immediately after isolation, and delivered frozen. MBMMC are a mixed population of cells that include hematopoietic stem cells and progenitor cells, monocytes, and lymphocytes. Each vial contains at least 10 million cells in 1 ml volume. MBMMC are quality control tested for viability. MBMMC are negative for mycoplasma, bacteria, yeast, and fungi. MBMMC can be maintained for a short period of time in culture using the conditions provided by ScienCell Research Laboratories. MBMMC are not intended for long-term culture and should be used promptly for experiments.

Recommended Medium

It is recommended to use HematoGro Medium (HemGM, Cat. #5501) for short-term maintenance of MBMMC in vitro.

骨髓单个核细胞（BMMC）位于骨髓中，具有一定的再生潜能。原代BMMC是一类异质性的单核细胞群体，包括造血干细胞、造血祖细胞、未成熟单核细胞以及未成熟淋巴细胞。近年来的研究表明，BMMC可作为细胞治疗手段，用于治疗多种疾病，如心血管疾病、1型糖尿病和缺血性卒中。此外，BMMC还可应用于骨组织工程研究。原代小鼠骨髓单个核细胞（MBMMC）可用于进一步研究其作为潜在细胞治疗手段的应用价值。

ScienCell Research Laboratories提供的小鼠骨髓单个核细胞（MBMMC）来源于健康成年CD-1小鼠骨髓。该细胞产品已去除红细胞和骨髓巨噬细胞，在分离后立即冷冻保存，并以冷冻状态运输。MBMMC为混合细胞群体，包括造血干细胞和祖细胞、单核细胞及淋巴细胞。每瓶至少含1,000万个细胞，体积为1 mL。所有MBMMC均经过活率质量检测，并确认不含支原体、细菌、酵母及真菌污染。在ScienCell提供的培养条件下，MBMMC可进行短期体外培养。MBMMC不适用于长期培养，建议尽快用于实验。

推荐培养基

建议使用HematoGro培养基（HemGM，产品编号：5501）对MBMMC进行短期体外维持培养。