人精囊平滑肌细胞
ScienCell Research Laboratories 的人精囊平滑肌细胞（HSVSMC）分离自人精囊组织。HSVSMC 以第 1 代（P1）冻存，并以冷冻状态运输。每瓶含有 >5 × 105 个细胞，体积为 1 ml。
The seminal vesicles are a pair of tubular glands located near the prostate that secrete fluid which helps compose the semen. The secretion from the seminal vesicles are vital for coagulation and pH of semen, sperm motility, and stability of sperm chromatin. The SV consists of three layers: the inner basal mucosal layer composed of simple cuboidal and pseudo-stratified columnar epithelial cells, the middle muscular layer formed by smooth muscle cells, and the outer layer made up of dense connective tissue. Contraction of the seminal vesicle smooth muscle cells (SVSMC) help to drive the fluid secretion into the ejaculatory duct. Studies have indicated that androgen receptor signaling in SVSMC help to reduce seminal vesicle epithelial cell proliferation and can prevent abnormal cell proliferation and hyperplasia. Human SVSMC (HSVSMC) can be used to further study the role of smooth muscle cells in seminal vesicle function and pathology.
HSVSMC from ScienCell Research Laboratories are isolated from human seminal vesicle. HSVSMC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. HSVSMC are characterized by immunofluorescence with antibodies specific to α-smooth muscle actin. HSVSMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HSVSMC are guaranteed to further expand for 5 population doublings under the conditions provided by ScienCell Research Laboratories.
Recommended Medium
It is recommended to use Smooth Muscle Cell Medium (SMCM, Cat. #1101) for culturing HSVSMC in vitro.
精囊是一对位于前列腺附近的管状腺体，可分泌参与精液组成的液体。精囊分泌液对精液的凝固和 pH 值、精子运动能力以及精子染色质稳定性均具有重要作用。精囊由三层组织构成：内层为黏膜层，由单层立方上皮细胞和假复层柱状上皮细胞组成；中层为肌肉层，主要由平滑肌细胞构成；外层为致密结缔组织。精囊平滑肌细胞（SVSMC）的收缩有助于将分泌液推入射精管。研究表明，SVSMC 中的雄激素受体信号通路有助于抑制精囊上皮细胞增殖，从而预防异常细胞增殖和组织增生。人精囊平滑肌细胞（HSVSMC）可用于进一步研究平滑肌细胞在精囊生理功能及相关病理过程中的作用。
ScienCell Research Laboratories 的人精囊平滑肌细胞（HSVSMC）分离自人精囊组织。HSVSMC 以第 1 代（P1）冻存，并以冷冻状态运输。每瓶含有 >5 × 105 个细胞，体积为 1 ml。HSVSMC 采用针对 α-平滑肌肌动蛋白（α-smooth muscle actin）的特异性抗体进行免疫荧光鉴定。HSVSMC 经检测对 HIV-1、HBV、HCV、支原体、细菌、酵母菌和真菌均呈阴性。在 ScienCell Research Laboratories 提供的培养条件下，HSVSMC 可进一步扩增 5 个群体倍增（population doublings）。
推荐培养基
推荐使用平滑肌细胞培养基（Smooth Muscle Cell Medium，SMCM，产品编号：1101）在体外培养 HSVSMC。
| 目录编号 | 4480 |
|---|---|
| 制造国家 | 美国 |
| 产品编码 | HSVSMC |
| 规格/数量 | >5 x 10^5 cells in 1 ml volume. |
| 产品用途 | 本产品仅供研究使用。未经批准，不得用于人体、动物或体外诊断程序。 |
| 储存 | 收到后请立即将细胞从干冰直接转移至液氮中，并在进行细胞培养实验前始终保存在液氮中。 |
| 运输 | 干冰。 |
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