Human Seminal Vesicle Epithelial Cells

The seminal vesicles (SV) are a pair of tubular glands located near the prostate and are essential to the urinary system. They function under androgen control to produce and secrete fluid into the ejaculatory duct. The SV consists of three layers: the inner basal mucosal layer composed of simple cuboidal and pseudo-stratified columnar epithelial cells, the middle muscular layer formed by smooth muscle cells, and the outer layer made up of dense connective tissue. Various pathological conditions can arise in the SV, including congenital SV cysts, seminal vesculitis, and primary and secondary neoplasms. Additionally, SV invasion is often used as a prognostic marker in prostate cancer. SV epithelial cells offer unique opportunities to study many features of the SV.

HSVEpiC from ScienCell Research Laboratories are isolated from human seminal vesicle tissue. HSVEpiC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10⁵ cells in 1 ml volume. HSVEpiC are characterized by immunofluorescence with antibody specific to cytokeratin-18 and/or cytokeratin-19. HSVEpiC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HSVEpiC are guaranteed to further expand for 15 population doublings under the conditions provided by ScienCell Research Laboratories.

Recommended Medium

It is recommended to use Epithelial Cell Medium-2 (EpiCM-2, Cat. #4121) for the culturing of HSVEpiC in vitro.