人扁桃体内皮细胞

The tonsils are part of the lymphatic system and are located in the pharynx. The tonsils are the immune system’s first defense against foreign pathogens and help to prevent respiratory and gastrointestinal infections. Tonsil endothelial cells (TEC) line the blood vessels and actively participate in fluid balance, cellular transport, and immunity. TEC also perform specialized functions for the tonsils including recruiting lymphocytes from the blood. Studies have shown that TEC express proteins that aid in lymphocyte adhesion and extravasation. Morphological and physiological changes in human TEC (HTEC) can lead to the development of tonsillitis. HTEC are a useful model for studying inflammation in the tonsils.

HTEC from ScienCell Research Laboratories are isolated from human tonsil. HTEC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10⁵ cells in 1 ml volume. HTEC are characterized by immunofluorescence with antibodies specific to vWF/Factor VIII and/or CD31 (PECAM1). HTEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HTEC are guaranteed to further expand for 10 population doublings under the conditions provided by ScienCell Research Laboratories.

Recommended Medium

It is recommended to use Endothelial Cell Medium (ECM, Cat. #1001) for culturing HTEC in vitro.

扁桃体属于淋巴系统的一部分，位于咽部，是免疫系统抵御外来病原体的第一道防线，有助于预防呼吸道和胃肠道感染。扁桃体内皮细胞（TEC）排列于血管内壁，积极参与液体平衡、细胞运输和免疫调节。此外，TEC 还在扁桃体中发挥特异性功能，包括从血液中募集淋巴细胞。研究表明，TEC 可表达促进淋巴细胞黏附和穿越血管内皮的相关蛋白。人扁桃体内皮细胞（HTEC）的形态和生理功能发生异常变化可能导致扁桃体炎。HTEC 可作为研究扁桃体炎症反应的重要细胞模型。

ScienCell Research Laboratories 的人扁桃体内皮细胞（HTEC）分离自人扁桃体组织。HTEC 以第 1 代（P1）冻存，并以冷冻状态运输。每瓶含有 >5 × 10⁵ 个细胞，体积为 1 ml。HTEC 采用针对血管性血友病因子（vWF）/凝血因子 VIII 和/或 CD31（PECAM1）的特异性抗体进行免疫荧光鉴定。HTEC 经检测对 HIV-1、HBV、HCV、支原体、细菌、酵母菌和真菌均呈阴性。在 ScienCell Research Laboratories 提供的培养条件下，HTEC 可进一步扩增 10 个群体倍增（population doublings）。

推荐培养基

推荐使用内皮细胞培养基（Endothelial Cell Medium，ECM，产品编号：1001）在体外培养 HTEC。

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