Ready-to-use 3D Human Renal Proximal Tubular Epithelial Spheroids

ScienCell’s ready-to-use 3D renal proximal tubular epithelial spheroids (SP-HRPTEpiS) display the differentiated epithelial cell marker CK18. Notably, SP3D-HRPTEpiS also have high ACE2 (angiotensin-converting enzyme 2) expression. Our RT-PCR analysis indicate elevated mRNA expression of the renal proximal transport molecule and transporters in 3D spheroids, compared to 2D monolayer. SP3D-HRPTEpiS, therefore, provide a physiological in vitro model to study kidney functions, and immune response of kidney cells to viruses.